IDO2 is a presumptive immunomodulatory gene based on its close structural relationship to IDO1 and its expression in a variety of antigen-presenting cell types. Both IDO1 and IDO2 will catabolize tryptophan to kynurenine. Biochemical studies indicate that both enzymes are similarly robust in catabolic activity, although the in vitro conditions required for IDO2 to manifest the same level of activity differ somewhat from IDO1. However, whether IDO2 is active as a tryptophan catabolizing enzyme in human dendritic cells has been disputed. Further work is needed to conclusively determine that IDO1 and IDO2 are similar in their preference for substrates and reaction pathways to generate product. A non-redundant function for IDO2 relative to IDO1 is suggested by their rather distinct expression patterns and response to extracellular stimuli.
Optimal dilution of the INDOL1 antibody should be determined by the researcher.
A portion of amino acids 200-350 was used as the immunogen for the INDOL1 antibody.
Aliquot the INDOL1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
欢迎广大客户咨询订货,在线QQ:3507623898(点击即可添加QQ好友咨询)
4000-520-616
NSJ Bioreagents已有20多年的历史。NSJ Bio提供领先的、广泛使用的单克隆抗体以及单克隆和多克隆抗体的所有领域的研究,包括肿瘤,肿瘤生物标志物,细胞凋亡,免疫学,细胞生物学和转录因子。产品提供多种规格,以更好地适应研究人员的测试需求和预算限制。
目前苏州蚂蚁淘生物科技有限公司获得了NSJ Bioreagents公司的在线销售权
部分产品
|
|
AreaOfResearch | |
---|---|
|
|
ABOAntibody/Antibodies | AngiogenesisAntibodies |
ApoptosisAntibodies | Apoptosis Marker Antibody/Antibodies |
AstrocyteAntibody/Antibodies | AutophagyAntibodies |
B-CellAntibody/Antibodies | BetaCellAntibody/Antibodies |
CalciumChannelAntibodies | CancerAntibodies |
CardiovascularAntibodies | Cell BIOLOGyAntibodies |
CellCycleAntibodies | Cellular Marker &EpitopeTagAntibodies |
CytokineAntibodies | DendriticCellAntibody/Antibodies |
Developmental BIOLOGyAntibodies | EndoplasmicReticulumAntibody/Antibodies |
EndosomeAntibody/Antibodies | Endosome Marker Antibody/Antibodies |
EndothelialAntibody/Antibodies | EndothelialCellAntibody/Antibodies |
EndothelialCell Marker Antibody/Antibodies | EpigeneticsAntibodies |
ERAntibody/Antibodies | ErythrocyteAntibody/Antibodies |
FollicularLymphomaAntibody/Antibodies | GranuloctyeAntibody/Antibody |
HairyCellLeukemiaAntibody/Antibodies | HepatocellularCarcinomaAntibody/Antibodies |
HepatocyteAntibody/Antibodies | Hepatocyte Marker Antibody/Antibodies |
HumanProteinMicroarrayValidatedAntibody/Antibodies | IgAntibody/Antibodies |
ImmunologyAntibodies | InnateImmunityAntibody/Antibodies |
IsotypeControlAntibody/Antibodies | LateEndosome Marker Antibody/Antibodies |
LeukocyteAntibody/Antibodies | LoADIngControlAntibody/Antibodies |
LymphocyteAntibody/Antibodies | MacrophageAntibody/Antibodies |
MantleCellAntibody/Antibodies | MelanomaAntibody/Antibodies |
MesenchymalCellAntibody/Antibodies | MetabolismAntibody/Antibodies |
MicroBIOLOGyAntibodies | MicrogliaAntibody/Antibodies |
MitochondriaAntibody/Antibodies | MitochondrialAntibody/Antibodies |
MonocyteAntibody/Antibodies | MyeloidCellAntibody/Antibodies |
NeuronalAntibody/Antibodies | Neuronal Marker Antibody/Antibodies |
NeuroscienceAntibodies | NeutrophilAntibody/Antibodies |
NF-kBAntibody/Antibodies | NKCellAntibody/Antibodies |
NuclearAntibody/Antibodies | PhosphoAntibody/Antibodies |
PlateletAntibody/Antibodies | PopularAntibodies |
ProliferationAntibody/Antibodies | RabbitMonoclonalAntibody/Antibodies |
RecombinantAntibody/Antibodies | RenalCellAntibody/Antibodies |
SignalTransductionAntibodies | SkeletalMuscleAntibody/Antibodies |
SmoothMuscleAntibody/Antibodies | StemCellAntibody/Antibodies |
StemCell Marker Antibody/Antibodies | T-CellAntibody/Antibodies |
ThyroidAntibody/Antibodies | TLRAntibodies&Related |
ZincTransporterAntibody/Antibodies |
|